Nutrigenetics the relation between Genes and nutrition APOA2 Dissertation

Nutrigenetics the relation between Genes and nutrition APOA2 concerning cardiovescular diseases - Dissertation Example Within the nutrition-related disorder context, the variations in genetics underline the varying risks of the diseases, in response to interventions or treatments, as well as in the successful prevention chances. In addition to knowledge of the specific responsible genes, nutrigenetics provides an explanation on how and to which level the nutrition-related disorders and traits are determined by the variations in genetics. Therefore, the major concern in this is the need to answer the question of which particular genes are responsible for a trait, as well as the particular variation in functional identity by which individuals exhibit differences for trait, and the ideal way through which the gained knowledge can be beneficial to the population. Nutrigenetics refers to the effect of variations in genetics on an individual’s optimal dietary requirements. Therefore, nutrigenetics can be regarded as the retrospective study of how variations in genetics, which include single nucleoti de polymorphisms (SNPs) in individuals, result in varied responses to particular nutrients. Researchers have always defined the candidate genes for a given disorder or trait and eventually went ahead to search for the variation in genes, and the approach has been referred to as ‘hypothesis-driven’ method, since the gene selection is done based on their respective functions, just like the lipoprotein genes is regarded as candidates for obesity disorder; whereas the genes for signaling insulin are considered to be candidates for diabetes.